ADA 2018: 盘点 ADA 大会中的中国之声

2018-06-23 10:44 来源:丁香园 作者:许佳曦
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美国当地时间 6 月 22 日, 2018 年美国糖尿病学会年会(ADA2018)在美国佛罗里达州中部的著名城市——奥兰多(Orlando)拉开大幕。

据悉,本届大会吸引了超过 16000 余位全球糖尿病学领域相关专业的专家、学者齐聚一堂,对超过 3000 项原创研究的展示进行共同学习和讨论。

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戳我进入 2018 ADA 专题页面,了解更多精彩会议内容!

ADA 会议作为全世界范围内著名的糖尿病学会议,今年会议的主题是「DIABETES BREAKTHROUGHS HAPPEN HERE」,贯彻了 ADA 一贯的创新突破精神,同时也预示着本届学术盛宴将会呈现的精彩纷呈。

在本次 ADA 会议中,包括 375 场口头报告、2117 场壁报演讲,其中,中国学者也贡献了大量的研究进展,根据目前已有资料,我国入选的口头报告有 15 项,现在就和大家一起看看 ADA2018 上的中国之声:

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图 1 2018 ADA「中国之声」再续

1. 脂肪特异性生长激素受体敲除(AdGHRKO)对小鼠葡萄糖代谢的影响

The Maternal Impact of AdGHRKO Mice on Glucose Metabolism

XIAOSHUANG WANG, AI MI, YANSHUANG LIU, DAN WANG, LIYUAN RAN, YINGJIE WU, Dalian, China

2. Caveolin-1 缺陷保护胰岛β细胞免受棕榈酸引起的功能障碍和细胞凋亡

Caveolin-1 Deficiency Protects Pancreatic ß Cells against Palmitate-Induced Dysfunction and Apoptosis

WEN ZENG, KUNYING LIU, JIANSONG TANG, HAICHENG LI, HAIXIA XU, HONGYUN LU, HANGYA PENG, CHUWEN LIN, RILI GAO, SHUO LIN, KEYI LIN, YAN JIANG, LONGYI ZENG, Guangzhou, China

3. 1 型糖尿病患者的 CD24 hiCD38 hiβ细胞比例下降及其调节能力下降

Decrease in Proportion of CD24 hiCD38 hi Beta Cells and Impairment of Their Regulatory Capacity in Type 1 Diabetes Patients

YUESHU WANG, XING WANG, YAO QIN, MEI ZHANG, Nanjing, China

4. 生活方式干预降低中国成人心血管疾病的 IGT-30 年随访大庆糖尿病预防研究

Lifestyle Interventions Lower Cardiovascular Disease in Chinese Adults with IGT—Thirty-Year Follow-Up of Da Qing Diabetes Prevention Study

QIUHONG GONG, PING ZHANG, JIXIANG MA, JINPING WANG, YALI AN, YILING J. CHENG, BO ZHANG, HUI LI, YANYAN CHEN, YINGHUA HU, EDWARD W. GREGG, PETER H. BENNETT, GUANGWEI LI, Beijing, China, Atlanta, GA, Daqing, China, Phoenix, AZ

5. 线粒体甘油 3-磷酸脱氢酶改善肥胖和糖尿病中的骨骼肌再生

Mitochondrial Glycerol 3-Phosphate Dehydrogenase Improves Skeletal Muscle Regeneration in Obesity and Diabetes

HUA QU, YI ZHENG, Chongqing, China

6. SGLT2 抑制剂和 2 型糖尿病患者的中风风险 - 系统评价和 Meta 分析

SGLT2 Inhibitors and Stroke Risk in Patients with Type 2 Diabetes—A Systematic Review and Meta-analysis

MAN GUO, YONG XU, CHENLIN GAO, Luzhou, China

7. 血清成纤维细胞生长因子-21 与动脉粥样硬化相关,与非酒精性脂肪性肝病无关,并预测事件性动脉粥样硬化性心血管疾病

Serum Fibroblast Growth Factor-21 Is Related to Atherosclerosis Independent of Nonalcoholic Fatty Liver Disease and Predicts Incident Atherosclerotic Cardiovascular Diseases

LIANG WU, LINGLING QIAN, HUATING LI, WEIPING JIA, Shanghai, China

8. 胎盘生长因子激活褐变脂肪组织

Activation of Browning Adipose Tissues by Placental Growth Factor

RUILI YIN, JING ZHOU, CHUANHAI ZHANG, CEN YAN, WEI MA, NANNAN WU, DONG ZHAO, YINGMEI FENG, Beijing, China

9. 基于全基因组关联研究的中国汉族人群自身抗体阳性 1 型糖尿病 HLA-C 位点定位

HLA-C Position 275, a Novel HLA Locus Identified in Autoantibody-Positive Type 1 Diabetes of Chinese Han Population Based on a Genome-Wide Association Study

HENG CHEN, YUN SHI, YUN CAI, HAO DAI, SHUAI ZHENG, XUQIN ZHENG, HONGWEN ZHOU, LIPING YU, ZHIBIN HU, ZHIGUANG ZHOU, JIANPING WENG, HONGBING SHEN, TAO YANG, Nanjing, China, Aurora, CO, Changsha, China, Guangzhou, China, Jiangsu, China

10. BAF60a 在棕色脂肪中协调热致染色质的可行性

BAF60a Orchestrates Thermogenic Chromatin Accessibility in Brown Fat

SIMING LI, TONGYU LIU, LIN MI, ZHUOXIAN MENG, JIANDIE LIN, Ann Arbor, MI, Hangzhou, China

11. 内质网膜蛋白复合物 10(EMC10),一种用于系统能量和代谢稳态的新型循环因子

Endoplasmic Reticulum Membrane Protein Complex 10 (EMC10), a Novel Circulating Factor for Systemic Energy and Metabolic Homeostasis

XUANCHUN WANG, GUIFEN QIANG, YANLIANG LI, XINYI CAO, VICTORIA GIL, SHENGXIAN LI, KUANGYANG CHEN, XINRU WANG, MATTHIAS BLUHER, CHONG WEE LIEW, Shanghai, China, Beijing, China, Chicago, IL, Leipzig, Germany

12. 血管生成素样蛋白 3 直接调节高密度脂蛋白(HDL)代谢和功能

Angiopoietin-Like Protein 3 Directly Regulates HDL Metabolism and Function

LONGYAN YANG, YAN WANG, YING FU, JIANAN LANG, DONG ZHAO, YINGMEI FENG, Beijing, China

13. 高血糖合并血脂异常患者循环 ANGPTL8 和 ANGPTL4 水平升高 

Circulating ANGPTL8 and ANGPTL4 Levels Are Increased in Patients with Hyperglycemia Combined Dyslipidemia

XUEFENG YU, PUHAN LU, XI CHEN, Wuhan, China

14. 新型纳米材料对葡萄糖和脂质代谢的影响

Effect of a New Type of Nanomaterial on Glucose and Lipid Metabolism

JIN WU, YINGBO CHEN, LIPING LIU, QING YAO, XIAOCEN LIU, YINGJIE WU,  Dalian, China, Jinan, China

15. CMHX008 是一种新型噻唑烷二酮样 PPARγ部分激动剂,在增强胰岛素敏感性的同时对骨量丢失的影响小

CMHX008, a Novel Thiazolidinedione-Like PPARγ Partial Agonist, Enhances Insulin Sensitivity with Minor Influences on Bone Loss

XIAOQIU XIAO, YI HOU, XUEMEI CAO, JIAYU LI, Chongqing, China

在上述口头报告之外,也有多篇中国学者的学术研究进展通过壁报的形式进行汇报展示。此外中国糖尿病协会也与 ADA 大会进行合作,联合举办了一场关于葡萄糖和脂质代谢新机制与靶点的研讨会。

会议主题:ADA / 中国糖尿病协会联合座谈会 – 关于葡萄糖和脂质代谢的新机制和新靶点

Joint ADA/Chinses Diabetes Society Symposium-Glucose and Lipid Metabolism-Novel Mechanisms and Targets

Co-Chairs: Weiping Jia, MD, PhD and Ling Qi, PhD

1. cGAS Pathway Activation in Obesity-Induced Metabolic Dysfunction

Feng Liu, MD, PhD

2. Mitochondrial Dynamics and Hepatic Metabolism

Chih-Hao Lee, PhD

3. The Role of SGLT2 in Diabetes-Associated Hypertension

Zhiming Zhu, MD

4. The Role of Ubiquitination Regulation in Insulin Resistance

Xiaoying Li, MD, PhD

5. Ameliorating Diabetic Nephropathy by Transcriptional Suppression of TGFß1

Junli Liu, PhD

6. Question and Discussion Period

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图 2 第 79 届美国糖尿病协会(ADA)科学年会预告

遗憾未能到场参会倾听或发出「中国之声」的同道们可以为 2019 年的行程提前做准备了!还想了解更多本次年会的内容?更多专家口头汇报的详细内容以及壁报演讲将在未来几天陆续公开,丁香园将持续进行关注和报道,及时给您带来更多 ADA 中国专家相关的精彩资讯,与您共同关注糖尿病的新热点与新进展!

文中照片拍摄自会议现场

编辑: 蒋辛培

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