依据艾美仕市场研究公司最新的数据，美国处方量最大和销售额最高的处方药较前没有明显改变。
治疗甲状腺功能减退药物左旋甲状腺素（Synthroid，艾伯维）仍然是全国处方量最大的药物，而抗精神病药物阿立哌唑（Abilify，大冢制药）则继续保持美国销售额最高处方药的桂冠。
这些数据反映了过去12个月期间（2013年07月至2014年06月）美国处方量和销售额前100名药物情况。
作为美国处方量最大药物，过去12个月期间，美国开出了2260万张左旋甲状腺素处方。继左旋甲状腺素钠之后是降胆固醇药物瑞舒伐他汀（Crestor，阿斯利康），大约有2250万张处方；第三名是质子泵抑制剂埃索美拉唑（Nexium，阿斯利康），约有1860万张处方；治疗哮喘药物沙丁胺醇（Ventolin HFA，葛兰素史克）以1750万张处方排名第四；而丙酸氟替卡松/沙美特罗吸入剂（Advair Diskus，葛兰素史克）则以1500万张处方排名第五。
美国处方量最大药物排名前10的其他5种药物分别为：抗高血压药缬沙坦（代文，诺华）；降血糖药甘精胰岛素注射液（来得时，赛诺菲安万特）；抗抑郁药度洛西汀（欣百达，礼来）；治疗注意力缺陷药物二甲磺酸赖右苯丙胺（Vyvanse，夏尔公司）；以及抗癫痫药普瑞巴林（Lyrica，辉瑞）。
作为美国销售额最高的处方药，2013年07月至2014年06月期间，阿立哌唑销售额高达72亿美元。其次是关节炎治疗药物阿达木单抗（Humira，艾伯维），63亿美元；埃索美拉唑（Nexium，阿斯利康），63亿美元；瑞舒伐他汀（Crestor，阿斯利康），56亿美元；以及关节炎治疗药物依那西普（恩利，安进公司），接近51亿美元。
美国销售额最高药物排名前10的其他5种药物分别为：丙酸氟替卡松/沙美特罗吸入剂（Advair Diskus，葛兰素史克），50亿美元；抗病毒药索菲布韦（Sovaldi，吉利德公司），44亿美元；关节炎治疗药物英利昔单抗（类克，山陶克公司），43亿美元；降血糖药甘精胰岛素注射液（来得时，赛诺菲安万特），38亿美元；以及中性粒细胞减少症治疗药物聚乙二醇非格司亭（Neulasta，安进公司），接近37亿美元。
表1 美国月处方量前100名药物
排名 | 药名（商品名） | 2013.7–2014.6期间总处方量 |
1 | Synthroid | 22,664,826 |
2 | Crestor | 22,557,735 |
3 | Nexium | 18,656,464 |
4 | Ventolin HFA | 17,556,646 |
5 | Advair Diskus | 15,003,169 |
6 | Diovan | 11,401,503 |
7 | Lantus Solostar | 10,154,739 |
8 | Cymbalta | 10,065,788 |
9 | Vyvanse | 10,019,178 |
10 | Lyrica | 9,684,884 |
11 | Spiriva Handihaler | 9,518,849 |
12 | Lantus | 9,358,961 |
13 | Celebrex | 8,815,391 |
14 | Abilify | 8,777,842 |
15 | Januvia | 8,758,309 |
16 | Namenda | 7,640,319 |
17 | Viagra | 7,584,152 |
18 | Cialis | 7,555,933 |
19 | Zetia | 7,411,629 |
20 | Nasonex | 7,304,210 |
21 | Suboxone | 7,011,882 |
22 | Symbicort | 6,948,403 |
23 | Bystolic | 6,722,578 |
24 | Flovent HFA | 5,623,533 |
25 | Oxycontin | 5,559,330 |
26 | Levemir | 5,554,827 |
27 | Xarelto | 5,014,364 |
28 | Nuvaring | 5,011,966 |
29 | Dexilant | 4,866,178 |
30 | Thyroid | 4,834,481 |
31 | Benicar | 4,725,628 |
32 | Voltaren Gel | 4,709,766 |
33 | Proventil HFA | 4,494,004 |
34 | Tamiflu | 4,149,835 |
35 | Novolog | 4,044,310 |
36 | Novolog Flexpen | 4,006,690 |
37 | Premarin | 3,984,357 |
38 | Vesicare | 3,873,046 |
39 | Humalog | 3,858,256 |
40 | Benicar HCT | 3,633,026 |
41 | Lumigan | 3,283,060 |
42 | Afluria | 3,242,605 |
43 | Lo Loestrin Fe | 3,154,488 |
44 | Janumet | 3,089,749 |
45 | Ortho-Tri-Cy Lo 28 | 3,053,738 |
46 | Toprol-XL | 3,044,003 |
47 | Pristiq | 3,023,546 |
48 | Combivent Respimat | 2,994,490 |
49 | Vytorin | 2,988,460 |
50 | Travatan Z | 2,919,358 |
51 | Focalin XR | 2,866,278 |
52 | Pataday | 2,757,094 |
53 | Humalog Kwikpen | 2,626,530 |
54 | Lunesta | 2,590,519 |
55 | Avodart | 2,527,583 |
56 | Pradaxa | 2,442,678 |
57 | Seroquel XR | 2,405,130 |
58 | Strattera | 2,387,756 |
59 | Minastrin 24 Fe | 2,353,282 |
60 | Evista | 2,232,555 |
61 | Chantix | 2,151,879 |
62 | Zostavax | 2,145,562 |
63 | Humira | 1,923,427 |
64 | Victoza 3-Pak | 1,902,995 |
65 | Exelon | 1,877,942 |
66 | Exforge | 1,838,730 |
67 | Combigan | 1,821,491 |
68 | Dulera | 1,790,677 |
69 | Onglyza | 1,784,018 |
70 | Welchol | 1,778,218 |
71 | Premarin Vaginal | 1,718,405 |
72 | Enbrel | 1,627,480 |
73 | Xopenex HFA | 1,588,895 |
74 | Ranexa | 1,567,961 |
75 | Truvada | 1,532,734 |
76 | Alphagan P | 1,503,194 |
77 | Viibryd | 1,447,730 |
78 | Tradjenta | 1,443,791 |
79 | Effient | 1,434,572 |
80 | Azor | 1,433,045 |
81 | Norvir | 1,384,306 |
82 | Actonel | 1,339,615 |
83 | Namenda XR | 1,319,963 |
84 | Amitiza | 1,309,980 |
85 | Aggrenox | 1,286,826 |
86 | Lotemax | 1,276,480 |
87 | Patanol | 1,274,050 |
88 | Levitra | 1,273,311 |
89 | Advair HFA | 1,272,551 |
90 | Uloric | 1,244,536 |
91 | Detrol La | 1,225,506 |
92 | Asmanex Twisthaler | 1,219,112 |
93 | Lipitor | 1,212,376 |
94 | Atripla | 1,183,636 |
95 | Prempro Low Dose | 1,162,513 |
96 | Latuda | 1,123,396 |
7 | Novolog Flxpen Mix 70/30 | 1,119,855 |
98 | Invokana | 1,106,268 |
99 | Epiduo | 1,103,330 |
100 | Humulin N | 1,071,673 |
表1 美国销售额前100名药物
排名 | 药名（商品名） | 2013.7–2014.6期间总销售额 |
1 | Abilify | $7,240,043,661 |
2 | Humira | $6,310,742,887 |
3 | Nexium | $6,303,738,580 |
4 | Crestor | $5,672,991,435 |
5 | Enbrel | $5,097,263,350 |
6 | Advair Diskus | $5,064,138,456 |
7 | Sovaldi | $4,469,558,675 |
8 | Remicade | $4,342,356,359 |
9 | Lantus Solostar | $3,829,943,226 |
10 | Neulasta | $3,688,450,342 |
11 | Copaxone | $3,677,307,402 |
12 | Rituxan | $3,361,247,463 |
13 | Spiriva Handihaler | $3,270,501,346 |
14 | Januvia | $3,124,826,108 |
15 | Lantus | $3,011,654,746 |
16 | Atripla | $2,898,264,003 |
17 | Cymbalta | $2,839,722,673 |
18 | Avastin | $2,784,813,413 |
19 | Lyrica | $2,782,036,977 |
20 | Oxycontin | $2,524,152,087 |
21 | Celebrex | $2,435,800,107 |
22 | Epogen | $2,378,212,523 |
23 | Truvada | $2,351,681,656 |
24 | Diovan | $2,177,824,165 |
25 | Levemir | $2,121,663,090 |
26 | Gleevec | $2,087,891,457 |
27 | Herceptin | $2,032,270,434 |
28 | Vyvanse | $1,940,313,035 |
29 | Lucentis | $1,932,528,073 |
30 | Zetia | $1,930,143,528 |
31 | Tecfidera | $1,908,407,807 |
32 | Symbicort | $1,901,446,790 |
33 | Namenda | $1,774,338,290 |
34 | Novolog Flexpen | $1,720,294,797 |
35 | Xarelto | $1,546,602,955 |
36 | Novolog | $1,466,291,783 |
37 | Humalog | $1,418,795,789 |
38 | Suboxone | $1,388,999,843 |
39 | Tysabri | $1,315,848,323 |
40 | Viagra | $1,274,239,087 |
41 | Seroquel XR | $1,266,841,322 |
42 | Victoza 3-Pak | $1,263,623,179 |
43 | Cialis | $1,241,580,547 |
44 | Stelara | $1,221,329,301 |
45 | Alimta | $1,215,044,019 |
46 | Nasonex | $1,190,958,069 |
47 | Avonex | $1,146,712,504 |
48 | Gilenya | $1,143,648,903 |
49 | Humalog Kwikpen | $1,140,418,800 |
50 | Flovent HFA | $1,091,998,384 |
51 | Prezista | $1,079,469,740 |
52 | Janumet | $1,071,110,813 |
53 | Renvela | $1,063,062,816 |
54 | Isentress | $1,045,929,798 |
55 | Procrit | $1,028,448,101 |
56 | Orencia | $1,017,584,725 |
57 | Dexilant | $1,010,512,519 |
58 | Vesicare | $1,001,127,504 |
59 | Stribild | $962,264,200 |
60 | Olysio | $943,547,154 |
61 | Synthroid | $927,886,999 |
62 | Neupogen | $922,013,084 |
63 | Avonex Pen | $920,097,484 |
64 | Reyataz | $918,922,508 |
65 | Zytiga | $918,603,420 |
66 | Xolair | $902,375,287 |
67 | Invega Sustenna | $891,518,099 |
68 | Benicar | $884,750,288 |
69 | Combivent Respimat | $881,992,234 |
70 | Pradaxa | $879,463,846 |
71 | Sensipar | $878,283,696 |
72 | Xgeva | $844,140,641 |
73 | Vytorin | $828,020,808 |
74 | Betaseron | $824,758,830 |
75 | Aranesp | $824,531,232 |
76 | Prevnar 13 | $818,701,788 |
77 | Latuda | $803,311,039 |
78 | Afinitor | $800,598,342 |
79 | Lunesta | $778,412,409 |
80 | Ventolin HFA | $771,201,081 |
81 | Complera | $756,268,942 |
82 | Synagis | $754,510,179 |
83 | Bystolic | $736,654,176 |
84 | Zyvox | $733,964,492 |
85 | Gardasil | $717,881,961 |
86 | Sandostatin Lar | $715,506,378 |
87 | Benicar HCT | $699,679,537 |
88 | Treanda | $692,288,820 |
89 | Pristiq | $687,192,710 |
90 | Zostavax | $674,280,328 |
91 | Erbitux | $669,382,439 |
92 | Cimzia | $660,599,949 |
93 | Strattera | $658,818,959 |
94 | Cubicin | $655,269,663 |
95 | Xeloda | $652,443,257 |
96 | Tarceva | $638,909,500 |
7 | Evista | $638,155,000 |
98 | Velcade | $636,704,153 |
99 | Sprycel | $635,192,399 |
100 | Abraxane | $634,678,206 |
